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Mk-677 as a PCT: Keep Your Gains After a Cycle

Mk-677 as a PCT: Keep Your Gains After a Cycle

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The idea of using MK-677 as a PCT, either standalone or alongside a SERM, stems from its properties of increased recovery, healing, and muscle building in conjunction with the mildness of its side effects.

MK 677 will help preserve the hard-earned muscle you built during your cycle and improve your sleep, appetite, and general quality of life for the duration of your PCT. If taken alongside a SERM, it will also mitigate the decrease in IGF-1 that SERMs cause and further contribute to your recovery.

This article is a comprehensive guide on incorporating MK-677 as a standalone PCT compound, or alongside a SERM. It is based on the latest academic data, the careful analysis of thousands of online anecdotal reports and experiences, and my own experiments on myself and over 500 lifetime clients.

Enjoy.

What is MK-677: Mechanism of Action

MK-677 is an oral GH and IGF-1 secretagogue. Meaning that it promotes the production of growth hormone and IGF -1. Two of the most anabolic hormones in the body.

MK 677 does this by attaching to Ghrelin receptors and mimicking the hormone ghrelin, which is responsible for making you feel hungry. It binds to GHSR in the brain to raise circulating levels of GH and IGF-1 throughout the body.

Benefits

The clinically proven benefits of MK-677 include:

  • Increased Muscle Growth
  • Increased Strength and Performance
  • Fat Loss (Through Lipolysis)
  • Increased Bone, Joint, and Connective Tissue Strength & Recovery
  • Increased Recovery & Healing
  • Increased Hunger
  • Drastically Better Sleep
  • Better Nutrient Partitioning

Side Effects

While considered mild, MK-677 can have side effects that can lead to serious issues if it’s for prolonged periods of time at high dosages.

For the purpose of using it as a PCT though, they are not applicable. Regardless, you should still be aware of them before even considering taking MK-677 for whatever reason. 

The side effects of MK-677 include:

  • Water Retention
  • Lethargy, often reported on doses above 15 mg/day
  • Increased Prolactin
  • High Blood Sugar & Insulin Resistance

If you want to learn more about what you can do to prevent these side effects, navigate to my dedicated guide on MK-677 by clicking the highlighted text.

MK-677 as a PCT

MK 677 is not a replacement for a proper PCT with a SERM after a suppressive cycle.

The point of a PCT is to jumpstart your endogenous testosterone production after a suppressive cycle. Only a SERM is capable of fulfilling that purpose. MK-677 will not help you recover your natural testosterone in any way.

Before you decide to use it as a standalone PCT you must know the extent of your testosterone suppression based on the SARM you took, and your post-cycle-bloodwork.

MK-677 can only be used as a standalone PCT after mild cycles of Ostarine, Andarine, or ACP 105, where the testosterone suppression is mild and recoverable naturally – which should always be confirmed by bloodwork.

Use this chart for reference:

BloodworkSuppression SymptomsPCT with SERM
Total Testosterone & LH within reference range (even if close to bottom)

No

Optional/No
Total Testosterone & LH within reference range (even if close to bottom) Yes Yes
Total Testosterone & LH below reference range Yes/No Yes
Can’t Do Bloodwork (For Whatever Reason) No Optional/No
Can’t Do Bloodwork (For Whatever Reason) Yes Yes

How to Do Bloodwork​

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MK-677 Alongside a SERM

For scenarios where a SERM is necessary based on bloodwork, MK-677 is a highly effective addition to it as a part of the overall PCT. This is the case after moderately and highly suppressive cycles.

It will further aid in the general recovery process by doing what it does, and also make up for the suppression of IGF-1 which SERMs are known to cause. In fact, using MK677 during SARM+SERM protocols is very common because of this.

How to Use MK 677 as a PCT

Using MK 677 as a PCT is very simple if you know how it works and how you would take it otherwise. There are no hard rules, and you can get creative with it as long as you don’t exceed 16 weeks of non-stop use or jump to high dosages. You can:

  1. Take MK 677 for the duration of the entire cycle and the PCT
  2. Take MK 677 after the cycle as a standalone PCT or alongside a SERM depending on the level of testosterone suppression
  3. Take MK-677 in a SARM + SERM protocol

Dosing Protocol

  • Half-life: Unclear
  • Dose: 10 – 20 mg/day
  • Frequency: 1x a day
  • Timing: Morning
  • Cycle Length: 8 – 16 weeks

Even though the half-life of MK677 has not been clinically solidified, once-per-day dosing has been successfully used as a viable frequency of administration throughout all of the clinical studies to date. Most clinical trials have been done in the dose range of 10 – 25 mg/day, which is also what most anecdotal users recommend as the sweet spot dose range.

As per dosing timing, you can take it any time during the day, as long as it’s the same time every day. If you want to avoid the increased hunger effect, take it at night.

US Vendors: Use “POP10” and “POP20” for a discount.

All ship worldwide, but shipping times may vary from the US.

SwissChems (Capsules)
AminoAsylum (Liquid)
Chemyo (Liquid)

UK & EU Vendors

Use “POP20” for a discount.

CamoChem (Liquid)

Examples:

WeekSARMMK-677SERM if applicable
1 x mg/day 10mg/day  
2 x mg/day 10mg/day
3 x mg/day 10mg/day
4 x mg/day 10mg/day  
5 x mg/day 10mg/day
6 x mg/day 10mg/day
7 x mg/day 10mg/day
8 x mg/day 10mg/day
9   15mg/day x mg/day
10   15mg/day x mg/day
11   15mg/day x mg/day
12   15mg/day x mg/day

Taking MK 677 during the entire cycle and PCT is ideal for bulking cycles where you want to leverage the increased hunger, along with the other benefits of MK 677. 

On 10 mg/day you will not experience any noticeable water retention or lethargy. During the PCT you can increase the dose to 15 mg/day.

Pro tip: be careful when stacking LGD 4033 and MK 677 as they both cause water retention which could get out of hand.

WeekSARMMK-677SERM if applicable
1 x mg/day
2 x mg/day
3 x mg/day
4 x mg/day
5 x mg/day
6 x mg/day
7 x mg/day
8 x mg/day
9 10 -15 mg/day x mg/day
10 10 -15 mg/day x mg/day
11 10 -15 mg/day x mg/day
12 10 -15 mg/day x mg/day

Take MK 677 after the cycle as a standalone PCT or with a SERM depending on the level of suppression. It will greatly aid in recovery and mitigate the IGF-1 suppression that a SERM would normally cause.

WeekSARMMK-677SERM if applicable
1 x mg/day
2 x mg/day
3 x mg/day
4 x mg/day 
5 x mg/day10 -15 mg/day

x mg/day

6 x mg/day

10 -15 mg/day

x mg/day

7 x mg/day

10 -15 mg/day

x mg/day

8 x mg/day

10 -15 mg/day

x mg/day

A SARM+SERM protocol is a new and experimental approach to cycling SARMs which is becoming increasingly popular as more and more users are reporting their successful experiences.

In a SARM+SERM protocol, the SERM is deployed as a test base to combat the suppression as it’s happening. MK  677 is an excellent addition to SARM+SERM cycles as it mitigates the IGF-1 suppression that SERMs cause. 

US Vendors

Use “POP10” and “POP20” for a discount.

SwissChems (Tamoxifen, Clomiphene, Raloxifene, Enclomiphene)
AminoAsylum (Tamoxifen, Clomiphene, Raloxifene, Enclomiphene)

UK & EU Vendors

Use “POP20” for a discount.

CamoChem (Enclomiphene)

Conclusion

MK 677 can be taken as a standalone PCT after mildly suppressive SARMs to help retain and even build muscle post-cycle. But it will not reverse testosterone suppression, which is why it should always be taken as an addition and not a replacement for a SERM after suppressive cycles.

Sources

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