The idea of using MK-677 as a PCT, either standalone after your cycle or alongside a SERM, stems from its properties of increased recovery, healing, and muscle building in conjunction with the mildness of its side effects.
MK-677 will help preserve the hard-earned muscle you built during your cycle and improve your sleep, appetite, and general quality of life for the duration of your PCT. If taken alongside a SERM, it will also mitigate the decrease in IGF-1 that SERMs cause and further contribute to your recovery.
In this article, you’ll learn how to use MK-677 as a PCT and help maintain the muscle gains you made during your cycle. It’s based on the latest academic data, which is linked at the very bottom, and the thousands of anecdotal reports on the web—as well as my own personal experiment with myself and my clients.
MK-677 is an oral GH and IGF-1 secretagogue, meaning that it promotes the production of growth hormone and IGF-1, two of the most anabolic hormones in the body.
MK-677 does this by attaching to Ghrelin receptors and mimicking the hormone ghrelin, which is responsible for making you feel hungry. It binds to GHSR in the brain to raise circulating levels of GH and IGF-1 throughout the body.
The clinically proven benefits of MK-677 include:
While considered mild, MK-677 can have side effects that can lead to serious issues if used for prolonged periods of time at high dosages.
For the purpose of using it as a PCT, however, these side effects are not applicable. Regardless, you should still be aware of them before even considering taking MK-677 for whatever reason.
The side effects of MK-677 include:
MK-677 is not a replacement for a proper PCT with a SERM after a suppressive cycle.
The point of a PCT is to jumpstart your endogenous testosterone production after a suppressive cycle. Only a SERM is capable of fulfilling that purpose. MK-677 will not help you recover your natural testosterone in any way.
On the other hand, MK-677 after any cycle, regardless of whether you take a SERM or not, will help you keep and build more muscle while improving your sleep, appetite, and overall quality of life. It works great with SERMs that you actually need to use to recover your natural T levels.
For scenarios where a SERM is necessary based on bloodwork, MK-677 is a highly effective addition to it as part of the overall PCT because SERMs suppress IGF-1, one of the most anabolic hormones.
So using MK-677 to reverse counteract that suppression is a great way to utilize its benefits in increasing IGF-1.
Using MK-677 as a PCT is very simple if you know how it works and how you would take it otherwise. If you don’t, you can read through my other articles or get The SARMs Wiki.
In a nutshell, you can take it from 10-25 mg/day for the duration of your whole cycle or just your PCT. This applies especially for SARM + SERM stacks in which you use the SERM on-cycle instead of after it as a PCT.
Even though the half-life of MK-677 is still unclear, as far as the research goes, once-per-day dosing has been successfully used as a viable frequency of administration throughout all of the clinical studies to date.
Most clinical trials have been done in the dose range of 10 – 25 mg/day, which is also what most anecdotal users recommend as the sweet spot dose range.
As for dosing timing, you can take it any time during the day, as long as it’s the same time every day. If you want to avoid the increased hunger effect, take it at night. time every day. If you want to avoid the increased hunger effect, take it at night.
| Week | SARM | MK-677 | SERM if applicable |
|---|---|---|---|
| 1 | x mg/day | 10 mg/day | |
| 2 | x mg/day | 10 mg/day | |
| 3 | x mg/day | 10 mg/day | |
| 4 | x mg/day | 10 mg/day | |
| 5 | x mg/day | 10 mg/day | |
| 6 | x mg/day | 10 mg/day | |
| 7 | x mg/day | 10 mg/day | |
| 8 | x mg/day | 10 mg/day | |
| 9 | 15 mg/day | x mg/day | |
| 10 | 15 mg/day | x mg/day | |
| 11 | 15 mg/day | x mg/day | |
| 12 | 15 mg/day | x mg/day |
Taking MK 677 during the entire cycle and PCT is ideal for bulking cycles where you want to leverage the increased hunger, along with the other benefits of MK 677. On 10 mg/day you will not experience any noticeable water retention or lethargy. During the PCT you can increase the dose to 15 mg/day or more.
Pro tip: be careful when stacking LGD 4033 and MK 677 as they both cause water retention which could get out of hand and turn you into a bloatlord, cause headaches, and increase blood pressure.
| Week | SARM | MK-677 | SERM if applicable |
|---|---|---|---|
| 1 | x mg/day | ||
| 2 | x mg/day | ||
| 3 | x mg/day | ||
| 4 | x mg/day | ||
| 5 | x mg/day | ||
| 6 | x mg/day | ||
| 7 | x mg/day | ||
| 8 | x mg/day | ||
| 9 | 10 – 15 mg/day | x mg/day | |
| 10 | 10 – 15 mg/day | x mg/day | |
| 11 | 10 – 15 mg/day | x mg/day | |
| 12 | 10 – 15 mg/day | x mg/day |
In this example we’re using MK-677 after the cycle as a recovery “supplement” or alongside our PCT with a SERM. It will greatly aid in recovery and mitigate the IGF-1 suppression that a SERM would normally cause.
| Week | SARM | MK-677 | SERM if applicable |
|---|---|---|---|
| 1 | x mg/day | ||
| 2 | x mg/day | ||
| 3 | x mg/day | ||
| 4 | x mg/day | ||
| 5 | x mg/day | 10 – 15 mg/day | x mg/day |
| 6 | x mg/day | 10 – 15 mg/day | x mg/day |
| 7 | x mg/day | 10 – 15 mg/day | x mg/day |
| 8 | x mg/day | 10 – 15 mg/day | x mg/day |
In this example we’re using MK-677 in a SARM+SERM protocol. The SERM is deployed as a test base to combat the suppression as it’s happening. MK-677 is an excellent addition to SARM+SERM for the same reason as it is during any SERM use – to reverse IGF-1 suppression.
In conclusion, MK-677 is a highly effective addition to your post-cycle therapy (PCT), whether used alone or alongside a SERM. Its properties of enhancing recovery, preserving muscle mass, and improving your overall quality of life make it an excellent choice for anyone looking to maintain their hard-earned gains after a cycle. While MK-677 won’t directly restore your natural testosterone levels, it plays a crucial role in mitigating the decrease in IGF-1 that SERMs can induce, further supporting your recovery.
premium resources
Everything you would ever want or need to know about SARMs to use and recover from them. Also includes other research chemicals.
An all-in-one guide that will teach you how each of the peptides works, how you can use them and find the perfect one (or stack) to reach your goals.
Wish there was ONE comprehensive, easy-to-read guide to get you fully informed on the safe and effective use of anabolic steroids?
Improve penile function, get harder fuller and longer-lasting erections, increase stamina in bed and last longer, go more rounds. All the good stuff.
A summary of everything you NEED to know about using PHs as safely as possible, supplements to stay as healthy as possible during cycles and how to recover (PCT).
A document I originally made for my clients. A neat map to the sphere of PEDs and supplements.
You'll receive the link and a once-a-week PED-related article in your inbox upon subscribing.
A special gift to all my email subscribers. The PED Dictionary is a DOC designed to help you navigate the world of enhanced bodybuilding. A game changer for beginners that want to learn more but don't know where to start, and a must-have handbook for even the most advanced enhanced researchers.
