The optimal proportion between free testosterone and estradiol is a subject of extensive discussion and debate within our community, and we haven’t really reached a definitive consensus.
Free Testosterone is particularly relevant because it is the form of Testosterone that is readily available to bond with various tissues, including muscles.
Unlike bound Testosterone (the difference between Total and Free Testosterone), which is constrained by Sex Hormone-Binding Globulin (SHBG), Free Testosterone can directly impact muscle growth and performance.
Estradiol, interestingly, also contributes to sex drive, muscle fiber growth, and muscle recovery after exercise, so it is not the devil that many people would want you to believe it is.
Having a good Free Testosterone to Estradiol ratio is the key to feeling good and having a healthy libido both on and off cycle, because having a bad ratio is what causes the typical side-effects like sexual dysfunction, gynecomastia, moodiness, and acne.
In a bodybuilding and performance enhancement context, the IDEAL ratio of Free Testosterone to Estradiol should be around 5:1 off-cycle, and up to 10:1 on-cycle. In other words, for every unit of Estradiol, we want to have around 10 units of Free Testosterone.
This is where it gets complicated.
In the United States, Free Testosterone is typically measured in ng/dl (nanograms per deciliter), whereas Estradiol is measured in pg/ml (picograms per milliliter).
10 pg/ml =1 ng/dl
Note that if youโre outside the US your bloodwork results may be in the same measurement unit, so all youโll have to do is divide the Free Testosterone levels with the Estradiol levels.
Example:
As you can imagine, nailing this ratio is extremely difficult, even if you are getting bloodwork done often and you use chemistry to regulate your Estradiol and Free Testosterone levels, hence why we call it “ideal”.
There is no need to be obsessive about it: Having a ratio anywhere between 5:1 and 10:1 is great, whether you are on or off-cycle. What you want to prevent is your ratio from falling below 5:1, because the lower it goes, the more likely you are to get estrogenic side-effects like gynecomastia, acne, moodiness, etcโฆ
One of the main things that swayed me off PEDs for a very long time was my OCD around having everything perfectly; unfortunately, the truth is that your body is best at regulating everything on itโs own. And when you take that into your own hands by introducing PEDs, sh*t happens.
Everything you would ever want or need to know about SARMs, and how to properly use, maximize, and recover from them.
The SARMs Wiki is the culmination of 7 years worth of knowledge coming from independent experimentation with myself and hundreds of my clients, probably thousands of hours of research, going through every study, and the online reports of thousands of SARMs and PED users.
If you're ready to spend 150$+ on SARM cycles, why not do it right from the very start and save yourself the troubles of dealing with the nuances and complications of PED use?
The Peptide Wiki is an all-in-one guide that will give you a deep understanding of how each peptide works and how you can use them correctly and find the perfect one (or stack) to reach your goals (16 Total Most Popular Peptides Covered).
Not only will you learn how these peptides work in your body, but you will also learn how to prevent their potential side-effects, and how to reconstitute, dose, and store use them correctly (super easy to mess this up).
If you're going to spend hundreds of $ on Peptides, you might as well do them right.
I wrote this ebook/document with one goal in mind: To share the info that has helped dozens of my clients completely turn their sex lives around.
Everything that I have to say on how to do bloodwork as an enhanced (or to be enhanced!) lifter.
Which markers to test, how to read the results, how often to get each marker tested, and more.
A document I originally made for my clients. A neat map to the sphere of PEDs and supplements.
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A special gift to all my email subscribers. The PED Dictionary is a DOC designed to help you navigate the world of enhanced bodybuilding. A game changer for beginners that want to learn more but don't know where to start, and a must-have handbook for even the most advanced enhanced researchers.ย