MK-677 Stacks: RAD-140, LGD-4033, Ostarine, Cardarine & More

MK 677 is one of the most synergistic research chemicals to stack alongside other PEDs. Which is one of the reasons it’s become one of the most popular PEDs in existence.

Why MK-677 works great with other compounds

Each PED stimulates muscle growth via a muscle-building pathway. Androgen-based PEDs like SARMs and AAS, stimulate muscle growth by attaching to androgen receptors.

Based on my own personal experiments with myself and dozens of clients taking multiple SARMs, that do the same thing is pointless – you can also observe this in the thousands of anecdotal reports of users who stacked SARMs of the same kinds like LGD with RAD or Ostarine with RAD and experience disproportionately more side effects than benefits. You can read about this in my article stacking for synnergy.

If you want to maximize results you would be wise to combine different PEDs in such a way that they support each other by working through different pathways. This is where MK-677 shines.

What to stack MK-677 with

The increase in GH and IGF-1 makes MK 677 extremely effective at muscle building, general recovery, and even fat loss through lipolysis. Paired with the mildness of its side effects, you get a truly exceptional compound for any game plan.

Depending on whether you’re planning a cutting or bulking cycle, your options will differ.

Needless to say, versatile SARMs like RAD 140 and Ostarine with MK-677 will be great for any game plan, LGD with MK-677 for bulking, and Cardarine with MK-677 for cutting.

Bulking Stacks

When it comes to bulking MK-677 can be taken with most of the SARMs for very decent results. Experienced users typically stack it with:

• RAD 140
• LGD 3303
• S4
• MK2866
• LGD 4033

Cutting Stacks

MK-677 is rarely used for cutting because users fear that the increase in hunger might sabotage their diet. This can be easily prevented by taking MK-677 a few hours before bed.

But what many also don’t know is that MK-677 is exceptional at accumulating fat loss through nutrient partitioning and lipolysis. This is also the same mechanism of action behind the popular fat loss peptide known as Frag 176-191.

Lipolysis on MK677 can only happen when insulin levels are low, which is best achieved through fasting. To leverage this property, and at the same time avoid hunger, take MK677 3 hours after your last meal, before bed followed by 3-4 hours of fasting the following morning.

For cutting, MK-677 works best with mildly and moderately strong SARMs like:

• S4
• MK2866
• RAD 140

Additionally other PEDs that synergistically act on different mechanisms that aid in fat loss can also be utilized. These include peroxisome proliferator-activated receptor (PPAR) agonists like:

• GW501516 (Cardarine)
• GW0742

and Rev-ErbA agonists like:

• SR9009
• SR9011

LGD 4033 + MK 677 Stack

Suitable for:

• Bulking

LGD 4033 and MK 677 make an incredible combo for beginners who want to explode in size while keeping side effects to a minimum.

Depending on the doses you decide to take, you might experience excess water retention which can be dealt with by lowering your carbohydrate and sodium intake, supplementing with potassium, and drinking more water.

On LGD 4033 and MK 677 you can expect to gain a few pounds within days and look much fuller and bigger. As you go through the cycle you will experience steady gains week by week.

To run this stack properly you need to know your exact daily calorie maintenance and use it with a small surplus so that you don’t end up looking fat and puffy.

This cycle will for most users, require a PCT since it utilizes LGD. You can also continue using MK-677 for the duration of the PCT to aid with recovery as well as counteract the IGF-1 suppression of the SERM.

RAD 140 + MK677 Stack

Suitable for:

• Bulking
• Cutting
• Recomping

MK677 and RAD 140 are an incredible combo for bulking for those that want to stay lean and vascular during their bulk while getting stronger from session to session.

RAD 140 will make you a lot stronger, much more than LGD 4033 would. It’s also dry, meaning that it will not retain any water and make you look puffy. MK 677 will enhance muscle building, aid in recovery, and allow for a greater caloric intake by increasing hunger.

If you want to take this cycle one step further you can increase the dose of RAD 140 to 15mg/day at the 4-week mark, but only if you tolerated 10 mg/day well.

This stack might also require a PCT for RAD-140. You can also continue using MK-677 for the duration of the PCT to aid with recovery as well as counteract the IGF-1 suppression of the SERM.

## Ostarine + MK677 Stack

Suitable For:

• Bulking
• Cutting
• Recomping

Ostarine and MK 677 make for a very effective yet mild bulking combination. Not as strong as the RAD 140 and LGD 4033 stacks, but, much safer and less suppressive.

You can expect to make noticeable gains and steady progress, but nothing crazy. Not everyone will need to PCT after Ostarine but having a SERM like Tamoxifen at hand is always recommended. If you run this stack as a cutting cycle, you are more likely to need a PCT as a caloric deficit will exacerbate testosterone suppression

You can also continue using MK-677 for the duration of the PCT to aid with recovery as well as counteract the IGF-1 suppression of the SERM.

SR9009 / GW501516 (Cardarine) + MK677

Suitable For:

• Cutting

SR9009 and MK677 are an effective non-suppressive cutting stack. You will lose a considerable amount of fat running these compounds together, while staying side effect free, healthy, and functional.

Cardarine (GW501516) can also be used as it has a longer half life, though the shorter half life of SR9009 should not be a problem considering the cancer risk from GW501516.

Conclusion

MK 677 is a very versatile compound that can be synergistically stacked with a variety of PEDs in almost any setting to achieve any objective: whether it be cutting, bulking, or recomp.

Its properties and mildness in terms of side effects open many doors and even make it a great supplementary compound in any cycle.

A document I originally made for my clients. A neat map to the sphere of PEDs and supplements.

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