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BPC-157 & TB-500 Dosage Protocols for Any Injury

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BPC-157 & TB-500 Dosage Protocols for Any Injury
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BPC 157 and TB 500 are two peptides famous for their ability to treat a wide range of injuries, including tendon or ligament ruptures, tears as well as bone fractures, burns, and wounds.

Both BPC 157 and TB 500 naturally occur in humans and animals. They play a variety of roles in the body, ranging from anti-inflammation and healing to gastric health. Athletes primarily use BPC 157 and TB 500 for their ability to rapidly heal an injury through a process known as “angiogenesis”.

This article is a comprehensive guide on using BPC 157 and TB 500 for treating injuries. It is based on the latest academic data – which you can find referenced at the very bottom of this article, the analysis of thousands of anecdotal reports and experiences online, as well as my own experiments with myself and my clients.

Dosage Protocols for BPC-157 and TB-500

BPC 157 and TB 500 don’t need to be cycled on and off. If trying to heal something or recover from an injury, you simply use them until you are healed.

You can dose BPC 157 and TB 500 simultaneously or separately.

I recommend dosing them separately as they have different half-lives and will need to be injected at different times for optimal results.

If you didn’t already know this, I’ve included a detailed breakdown of both compounds further down the article.

BPC 157 Protocol

BPC 157 can be injected or taken orally. Some prefer to take it orally for ease of use, but it’s much less effective and you’d have to take large amounts to get decent results.

This is not only less effective for threating the injury, but also expensive to sustain.

Injectable administration is preferable for treating injuries.

Injecting BPC 157 subcutaneously, close to the injured area is the most effective way to use it.

BPC 157 has incredible localized effects but mediocre systemic effects.

The injectable dose range for BPC 157 is:

  • 250mcg to 500mcg per day

You can inject once or twice a day. I advise for more frequent injections, but once a day will also work.

Use BPC 157 as long as needed to heal your injury. There is no need to cycle it.

TB 500 Protocol

The exact half-life of TB 500 is still unclear. We only know that it is considerably longer than BPC 157.

So daily injections are not required. It is recommended to do every other day injections, but every 3 days is also doable. This is the protocol most clinics follow.

Unlike BPC 157, TB 500 has incredible systemic effects. Meaning that it doesn’t matter where you inject it.

The recommended dosage range for TB 500 is:

  • 1 to 2mg every other day

If you’re trying to heal an injury, use TB 500 for as long as necessary.

When taking it for other purposes, many users benefit from cycling it for up to 8 weeks at a time.

How to Use BPC 157 and TB500 Together

The best way to use BPC 157 and TB 500 together is to simply dose them separately, as they have different half-lives.

Note: That doesn’t mean that you can’t inject them together. It’s as simple as mixing in TB 500 with your daily BPC 157 injections, but every other day.

IMPORTANT: BPC 157 and TB 500 come in powdered form. Before you can inject them you must reconstitute these peptides in bacteriostatic water!

Mechanisms of Action

BPC-157 and TB-500 share similar mechanisms of action; namely, for the purpose of treating injuries, they induce what is known as angiogenesis.

Angiogenesis is a biological process that involves the growth of new blood vessels from pre-existing ones. It is essential for wound healing and tissue repair, and whenever you sustain an injury, your body heals it via this process.

Both BPC 157 and TB 500 promote and induce angiogenesis, helping you heal injuries faster.

What is BPC 157

BPC 157 is derived from a naturally occurring sequence of amino acids found in gastric juices. When injected, BPC 157 induces angiogenesis locally. It also has properties that greatly aid cognitive, cardiovascular, and digestive health.

BPC 157 Benefits

  • Healing of Wounds, Burns, Bruises, Scars, and even Mosquito Bites (proven in pre-clinical studies and confirmed by empirical data) [1]
  • Healing of Bones – effectiveness is comparable to bone marrow graft treatment. [2]
  • Healing of Tendons – pre-clinical studies proved that BPC 157 heals tendons almost completely (even in rats that would have never recovered without it). Empirical data also confirms this with hundreds of reports of users that used BPC 157 to heal injured tendons even after years of pain. [2]
  • Healing of Muscles – pre-clinical studies proved BPC 157 to be effective at healing cut or torn muscles in rats. There are also many anecdotal cases of bodybuilders who used it to speed up recovery after an injury. [3]
  • Neuroprotection – multiple pre-clinical studies proved the effectiveness of BPC 157 at protecting the brain in rats. It can heal nerve damage and significantly reduce the aftermath of brain injuries. [4]
  • Improved Digestive Health – since it’s found in the gut, it makes sense that BPC 157 would improve gut health. Pre-clinical studies have shown BPC 157 to heal ulcers and fistulas while improving gut flora. Empirical evidence has also shown that it effectively treats Inflammatory Bowel Disease. [5]

BPC 157 Side Effects

  • Cancer Growth – BPC 157 induces angiogenesis (healing property), which is the formation of new blood vessels. This trait can speed up the rate at which cancer grows in individuals already suffering from it. [7]
  • Injection-Related Side Effects – many people don’t know how to inject peptides correctly, which can lead to scar tissue build-up, irritation, and other annoying side effects.

What is TB 500

TB 500 is a synthetic form of a naturally occurring peptide Thymosin Beta-4 (TB4) which can be found in many tissues in both humans and animals. TB4 has many roles, but its main ones are tissue regeneration and anti-inflammation.

One of the most studied roles of thymosin beta-4 is in wound healing. It promotes cell migration, angiogenesis (formation of new blood vessels), and downregulates inflammatory responses, thereby accelerating tissue repair.

TB 500 Benefits

  • Healing of Burns & Wounds – TB4 is proven effective at healing wounds, cuts, and burns (even more rapidly than BPC 157) by promoting the formation of new blood vessels (angiogenesis). It’s also effective at preventing scars and fibrosis. [8]
  • Healing of Bones & Ligaments – pre-clinical studies have proven TB 500’s effectiveness at speeding up the healing process of bone fractures and ligament injuries. Anecdotal reports of athletes who have deployed TB 500 to heal such injuries further confirm that these findings apply to humans as well. [9]
  • Neuroprotection – pre-clinical studies show that TB 500 might be effective at attenuating and preventing brain damage after injuries. [11]
  • Healing of Muscles – TB-500 is frequently said to enhance muscular development, strength, and endurance. It can undoubtedly repair muscle injuries and encourage the regeneration of muscle cells following exercise-induced stress, but there isn’t any conclusive evidence to support its ability to significantly enhance muscle growth and strength. [10]
  • Fights Hyperglycemia – TB 500 has been shown to improve insulin sensitivity. [12]
  • Cardioprotective – there is scientific data to support that TB 500 has cardioprotective traits, as it prevents fibrosis and cardiac ischemia. [12]

TB 500 Side Effects​

  • Cancer Risk – some studies have found increased levels of TB4 in cancer cells, which has led some scientists to believe that it plays a role in cancer development. What we do know for sure is that TB4 promotes angiogenesis, so it can also lead to growing existing tumors. [13]
  • Injection-Related Side Effects – many people don’t know how to correctly inject peptides, which often leads to skin irritation, scar tissue build-up, and other annoying effects.

In pathological conditions such as cancer, angiogenesis is often dysregulated, leading to the formation of abnormal blood vessels that support tumor growth and metastasis. Taking TB 500 if you have cancer is a very bad idea to say the least.

Conclusion

When taken together, BPC 157 and TB 500 create a synergy unlike any other, capable of healing injured tendons, ligaments, and even bones.

They have been extensively used and recommended by thousands of professional athletes, bodybuilders, and everyday people. There are thousands of anecdotal cases online showcasing their potential to heal injuries, which further supports the scientific data we have on them.

Most importantly, they are side effect free (unless you already have cancer). If you are over-concerned, you can opt to skip TB 500 and just use BPC 157. But, in my opinion, you should be alright taking both.

Good luck, and I wish you a speedy recovery!

References:

BPC-157

1. Healing of Wounds and Burns

2. Healing of Bones and Tendons

3. Healing of Muscles

4. Neuroprotection

5. Improved Digestive Health

6. Other Benefits

7. Cancer Growth

TB-500 (Thymosin Beta-4)

8. Healing of Wounds and Burns

9. Healing of Bones and Tendons

10. Muscle Growth

11. Neuroprotection

12. Other Benefits

13. Cancer Risk

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