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11-Ketotestosterone / 11-Oxo: Benefits, Side-effects & Dosing

11-Ketotestosterone / 11-Oxo: Benefits, Side-effects & Dosing

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11-ketotestosterone (11-KT) is a naturally occurring steroid hormone that plays a crucial role in the physiology of certain animals, including fish and reptiles. Even though we humans produce it in very small amounts, it does not really have play any relevant role in the human body, so why are we even discussing it?

Well, exogenous 11-Ketotestosterone can be an incredibly useful PED for bodybuilders looking to build muscle, get shredded and look harder without facing serious side-effects. In this article, we will be taking a look at its benefits and side-effects, as well as how to use it properly.

Mechanism of Action of 11-Ketotestosterone

Like every other AAS, 11-Keto builds muscle by attaching to androgen receptors and stimulating protein synthesis. However, 11-Keto has a unique property that makes it truly special: It can inhibit the production of cortisol from cortisone.

11-Keto accomplishes this by inhibiting an enzyme called HSD-11Ξ², which is responsible for that conversion. By doing this, 11-Keto reduces stress and promotes the release of stubborn body fat, facilitating its use for energy (which results in fat loss).

Benefits of 11-Ketotestosterone

Here are the key benefits of this AAS:

  • Increased Muscle Growth: While 11-Keto is nowhere near as powerful as some other AAS, it can still build a decent amount of muscle mass without causing any water retention in the process. Users of 11-Keto can expect modest but noticeable gains in lean muscle mass.
  • Fat Loss: 11-Keto can contribute to fat loss (specifically stubborn lower belly/back fat loss) through the aforementioned mechanism of action.
  • Androgenic Effects: Even though 11-Keto is not a DHT derivative, it appears to be quite androgenic. Users experience muscle-hardening effects and increased vascularity, similar to what DHT derivatives like Winstrol, Proviron, and Anavar provide. Increased libido and improved mood are often reported as well.

It is worth noting, however, that 11-Keto does not seem to increase physical strength or performance to a significant extent. This could be due to the fact that this AAS can dry out the joints and reduce their ability to support heavy weights.

Side Effects of 11-Ketotestosterone

Other than the negative effect on joint health that we’ve just discussed, 11-Ketotestosterone is also known for causing the following negative side-effects:

  • HPTA Suppression: 11-Keto will suppress Testosterone production and decrease fertility, but it does not appear to do so to the same extent as other more popular AAS. Many 11-Keto users report that they never need a PCT after using it.
  • Dyslipidemia: As with practically any AAS, 11-Keto users can expect good cholesterol (HDL) to decrease and bad cholesterol (LDL) to increase.
  • Androgenic Side-Effects: It is entirely possible for 11-Keto to cause hair loss and acne in users who are prone to these conditions.

While these side-effects seem relatively normal and manageable, we need to take into account the fact that 11-Ketotestosterone is not backed by as much research and anecdotal data as other AAS are, so other side-effects are also possible.

11-Ketotestosterone Dosage & Protocols

Unfortunately, finding 11-Ketotestosterone for sale is extremely hard. Luckily, we can buy its precursor hormone, which is 11-oxoandrostenedione (aka 11-Oxo). 11-Oxo is orally bioavailable, but users see the best results when using it topically.

Taking 200 to 300mg orally (or rubbing an equivalent amount of cream) daily (in 2 to 3 servings) provides great results without causing too much Testosterone suppression. It can be used for up to 8 weeks at a time, and even though many people manage to get away without doing a PCT, I would always recommend doing one.

None of my trusted sources offer 11-Oxo, but you can easily find it for sale in the USA, the UK and Europe with a quick google search.

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