What is HGH Fragment 176-191?
HGH Fragment 176-191 is a peptide known as one of the best fat burners in the realm of enhanced bodybuilding. It does everything that it’s promised to do while keeping you healthy and side effects free.
Frag 176-191 is a peptide derived from HGH (human growth hormone). HGH has many functions in the body and is made up of 191 amino acids. One of the functions of HGH is inducing the breakdown of fats through a process known as lipolysis. Out of its 191 amino acid chain, the portion responsible for lipolysis is from the 176th to the 191st amino acids.
By separating this part of amino acids from the chain that makes up HGH, we get Frag. 176-191. A peptide that holds the fat loss benefits of HGH without any of the other properties.
This article is a comprehensive guide on Frag 176-191 based the latest scientific literature as well as the mass analysis of hundreds of anecdotal reports and experiences online.
Enjoy.
You may have also heard of a different peptide AOD-9604 (Frag 177-191 + Tyrosine). It is often mislabelled as Frag 176-191 – and vice versa. They are incredibly similar, so, practically everything that applies to one, also applies to the other. Thus I will be quoting some studies done on AOD as a reference throughout the article.
Benefits
If you start digging through Reddit and other forums, you will find that many users claim that Frag 176-191 increased their IGF-1 levels, improved their appetite and sleep, and even improved their cholesterol levels.
All of this is false, and the scientific data on HGH frag is clear.
Frag 176-191 has only 1 scientifically proven property, which is fat loss. It was the sole reason it was created. This leads me to believe that the users that have made these reports were all sold something entirely different.
Anyways:
Fat Loss [1][A]
Frag 176-191 induces lipolysis, so it will have a significant impact on fat loss.
Lipolysis is the biochemical process of breaking down the stored fat in the body into smaller components like fatty acids and glycerol, which can be utilized as an energy source for various bodily functions.
So, Lipolysis causes the mobilization and use of fat cells as a source of energy. It can only be induced by fasting, but certain hormones will have an effect.
These include norepinephrine, HGH, cortisol, and more.
So in a nutshell Frag 176-191 will allow you to burn a lot more fat and use it as energy while you are fasting.
If you go to bodybuilding groups/forums online, you’ll soon find that people either love or hate this peptide (along with AOD -9604). Many simply don’t use it properly, or they unknowingly buy bunk or fake Frag 176-191.
If you look at users that got good quality Frag 176-191 and followed a proper, proven protocol (like the one in this article), you’ll see that they were mindblown at how effective it was for helping them lose fat.
Side Effects [2][A]
Frag 176-191 (and AOD-9604) is (almost) side-effect free. The only thing it will do in terms of “side effects” is a modest increase in blood glucose. This increase in blood glucose was proven to be safe in a study, and won’t cause any long-term insulin resistance issues like various GH peptides and secretagogues can.
Injection Related Side Effects
Since many people do not know how to inject peptides properly, it can lead to scar tissue buildup and other pesky, but inconsequential sides. There is a portion of this article dedicated on doing it properly.

P.S. Make sure the HGH Frag you’re getting is legit. These are my recommended sources for the highest-quality powder available:
Dosing Protocol & Proper Usage
The only way to get good results from Frag 176-191 is to follow the correct protocol.
Unlike with other PEDs, where if you miss something you’ll still get results, with Frag 176-191 you either get it right and get amazing results or you miss something and get absolutely no benefits at all.
This is the protocol that I have found to work the best, for both myself, my clients, and many others online is as follows:
Dose: 500mcg/day
Inject 250mcg after waking up, on an empty stomach. Follow up with a 4-hour fast. If you break the 4-hour fast even by 1 calorie you will ruin the effects of Frag 176-191.
Inject the second 250mcg right before bed, 3-4 hours after your last meal. So if you had dinner at 8 or 9 pm, inject at midnight.
After 20 days on this protocol, I personally like to take 10 days off. Then rinse and repeat as needed, based on my goals.
Note: This is not the only good protocol out there, this is just one that has been shown to be effective across a large sample size of users
Pro tip: if you want to maximize the effects of your Frag 176 191 cycle, do some exercise or cardio during the fasting period following your morning injection.
How to Inject It
Frag 176-191 has systematic effects, meaning that regardless of where you inject it, it will work. The easiest place to inject peptides is in your lower belly fat area.
Peptides are administered through subcutaneous injections. The needle should not reach any muscle tissue, and the peptide should be released into fat tissue.
Use a brand-new insulin needle (any needle with the following specifications will do):
- 28 to 31G
- 8 to 12 mm in length
P.S. HGH Frag is sold in powdered form, and before it can be injected, it must be reconstituted in bacteriostatic (BAC) water. Get BAC here:
Instructions:
- Wash your hands
- Clean the rubber stopper on the vial with alcohol
- Insert the needle into the vial slowly
- Turn the vial upside down and slowly pull the desired dose while making sure there are no major air bubbles or air gaps in between
- Disinfect injection site
- Pinch your skin and lift up
- Insert the needle at a 90 or 45-degree angle
- Slowly press the plunger and inject the peptide into your subcutaneous fat
- Remove needle (and dispose of accordingly!)
- Disinfect and massage the area with an alcohol wipe
- Done!
Conlcusion
HGH Frag 176-191 is a truly incredible peptide that does what its supposed to, while keeping you side effect free and healthy. If you are very strict with your protocol you will have a truly amazing experience with it.
References:
1. FAT LOSS:
- Edwards M, Mohiuddin SS. Biochemistry, Lipolysis
- The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice
- Detection and in vitro metabolism of AOD9604
- The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice
- Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone
- Metabolic Pharmaceuticals’s Obesity Trial Update: First 100 Subjects Complete The Phase 2B Trial Of AOD9604
- Obesity Pharmacotherapy: Current Perspectives and Future Directions
- Effects of oral administration of a synthetic fragment of human growth hormone on lipid metabolism
2. GENERAL SIDE-EFFECTS:
- Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment
- Hyperglycemic action of synthetic C-terminal fragments of human growth hormone
- Safety and Tolerability of the Hexadecapeptide AOD9604 in Humans
- Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone