What Is Ace-083? New Myostatin Inhibitor Explained

Myostatin inhibition is a truly fascinating subject. As you probably know, myostatin is the protein that limits how much muscle mass our bodies can grow. Inhibiting/reducing it can not only facilitate muscle growth but also help us break through plateaus and reach superhuman levels of muscularity.

What is ACE-031?

There are a few different myostatin inhibitors on the market, with the most popular ones being YK-11, ACE-031 and Follistatin 344. YK-11 and ACE-031 work by increasing the levels of follistatin, which is the protein that counteracts the effects of myostatin. Follistatin 344 is simply an exogenous form of follistatin that causes a direct decrease in myostatin levels.

ACE-083 is a relatively new and incredibly promising myostatin inhibitor that is starting to make waves in the underground enhanced bodybuilding community. Unlike the aforementioned myostatin inhibitors, ACE-083 has been shown to work in a localized way, meaning that it only lowers myostatin wherever we inject it.

This localized action has some advantages and disadvantages compared to traditional systemic myostatin inhibitors…

Pros’ of ACE-083 vs Other Myostatin Inhibitors:

• ACE-083 allows bodybuilders to bring up lagging muscle groups and sculpt their body in a more precise and balanced way.
• ACE-083 is unlikely to have a negative impact on joint function throughout the body, and may only affect the area where it’s injected.
• Unlike other MIs, ACE-083 is probably not going to have a major negative impact on fertility (high follistatin is linked to low FSH) since its effects are not systemic.
• There is some evidence to suggest that myostatin plays a role in preventing cardiac hypertrophy, meaning that the localized effects of ACE-083 are less likely to make it dangerous for the heart.

Cons of Ace-083 vs Other Myostatin Inhibitors:

• By acting locally, ACE-083 is not ideal for muscle monsters who want to lower myostatin systemically and maximize muscle growth throughout the body. Achieving something similar with ACE-083 would require many injections per day.
• Myostatin inhibition is known to facilitate fat loss. Since ACE-083 only works locally, it won’t have the same effect on fat loss as a systemic MI.

How to Use Ace-083 & Where to Get It

Since ACE-083 is still relatively new and there is virtually no data about its use in humans, it would be irresponsible of me to provide dosing guidelines. Furthermore, no research chemical vendors offer it yet. That being said, I expect it to hit the market in the coming years.

A document I originally made for my clients. A neat map to the sphere of PEDs and supplements.

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